South Harrison travels to undefeated St. Marys, while Bridgeport hosts 5-2 Keyser.
South Harrison hosts Sherman in the Class A MetroNews Game of the Week.
Morgantown is home against Wheeling Park, Bridgeport at North Marion and Fairmont Senior at Weir.
Morgantown is at No. 3 Musselman, while University travels to No. 11 St. Albans in Week 6.
A look at several Week 5 games in the area, including Fairmont Senior at University and Morgantown at Martinsburg.
A look at Fairmont Senior at Bridgeport, plus University has a key road contest in AAA at Wheeling Park.
On Wednesday, Morgantown, Wheeling and Elkins picked up wins.
Capital enters postseason play at 18-4 on the season, looking for a return trip to the state tournament.
Parkersburg is attempting to get back to the girls basketball state tournament for the first time since 1997.
Winfield is one of the girls basketball Class AA state tournament contenders in 2017.
Buckhannon-Upshur has several big wins in 2016-2017, looking for an eventual deeper state tournament run.
University is looking for first state tournament berth since 1994 and finds itself atop the MetroNews Power Index.
Parkersburg South moved to Region 4 and has a new girls basketball head coach in 2016-2017.
The quarterfinal games begin Thursday at the Charleston Civic Center.
Bridgeport looks to win back-to-back football championships for the first time in school history.
Bridgeport faces Wayne and Clay-Battelle is at St. Marys.
A look at three quarterfinal matchups this weekend from the area.
A look at games around the region for the opening round of the playoffs.
Playoff seeding and spots on the line in the final week of the regular season.
The MoHawk Bowl is one of the highlights in the region for week 10 of the high school football season.